195/50 is already borderline harsh if you ask me, then 205/45 is 6mm thinner so IMHO it will surely be harsh. But again comfort/harsh is subjective, many people now especially young ones seem to have very high tolerance for harshness, so yeah maybe I'm just getting old already.
I've used once before 195/50/15 on my CB5 like over 15 yrs ago when I was still much younger obviously and even then I didn't really like it much. Hence once finished I changed to 195/55/15, felt way much better without any much compromise on handling too (at least for my amateur slow driving). If you want thinner, like bro Vr2 suggested go with 205/50/15, that's the minimum I'd personally use as the sidewall height is still still above 10cm (10.2cm) compared to 195/50 at 9.8cm while 205/45 is only wafer thin 9.2cm.